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1

Quartz crystal biosensor for real-time kinetic analysis of interaction between human TNF-α and monoclonal antibodies

Yang Liu, Wei Zhang, Xiao Yu, Hongwu Zhang, Rui Zhao, DiHua Shangguan, Yan Li, Beifen Shen, Guoquan Liu

Journal:

Sensors and Actuators B: Chemical

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

2

A new format of bispecific antibody: highly efficient heterodimerization, expression and tumor cell lysis

Zhigang Xie, Ning Guo, Ming Yu, Meiru Hu, Beifen Shen

Journal:

Journal of Immunological Methods

Year:

2005

Language:

english

File:

PDF, 345 KB

english, 2005

3

Novel strategies for inhibition of the p38 MAPK pathway

Jiyan Zhang, Beifen Shen, Anning Lin

Journal:

Trends in Pharmacological Sciences

Year:

2007

Language:

english

File:

PDF, 370 KB

english, 2007

4

Metastasis-related miRNAs, active players in breast cancer invasion, and metastasis

Ming Shi, Dan Liu, Huijun Duan, Beifen Shen, Ning Guo

Journal:

Cancer and Metastasis Reviews

Year:

2010

Language:

english

File:

PDF, 456 KB

english, 2010

5

Single-stranded DNA aptamers that bind differentiated but not parental cells: subtractive systematic evolution of ligands by exponential enrichment

Chenglong Wang, Ming Zhang, Guang Yang, Dajing Zhang, Hongmei Ding, Huixing Wang, Ming Fan, Beifen Shen, Ningsheng Shao

Journal:

Journal of Biotechnology

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

6

Improving Trastuzumab's Stability Profile by Removing the Two Degradation Hotspots

Yang, Yuemei, Zhao, Jian, Geng, Shusheng, Hou, Chunmei, Li, Xingyin, Lang, Xiaoling, Qiao, Chunxia, Li, Yan, Feng, Jiannan, Lv, Ming, Shen, Beifen, Zhang, Boyan

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 938 KB

english, 2015

7

Monoclonal antibody, mAb 4C13, an effective detoxicant antibody against ricin poisoning

Dong, Na, Luo, Longlong, Wu, Junhua, Jia, Peiyuan, Li, Qian, Wang, Yuxia, Gao, Zhongcai, Peng, Hui, Lv, Ming, Huang, Chunqian, Feng, Jiannan, Li, Hua, Shan, Junjie, Han, Gang, Shen, Beifen

Journal:

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

8

Complement C5a regulates IL-17 by affecting the crosstalk between DC and γδ T cells in CLP-induced sepsis

Ruonan Xu, Renxi Wang, Gencheng Han, Jianan Wang, Guojiang Chen, Liyan Wang, Xia Li, Renfeng Guo, Beifen Shen, Yan Li

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 400 KB

english, 2010

9

In vivo identification of the interaction site of ErbB2 extracellular domain with its autoinhibitor

Pinliang Hu, Jiannan Feng, Tao Zhou, Jianing Wang, Baofeng Jing, Ming Yu, Meiru Hu, Xuemin Zhang, Beifen Shen, Ning Guo

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 458 KB

english, 2005

10

RNA aptamers specific for bovine thrombin

Xuemei Liu, Dajin Zhang, Guojun Cao, Guang Yang, Hongmei Ding, Gang Liu, Ming Fan, Beifen Shen, Ningsheng Shao

Journal:

Journal of Molecular Recognition

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

11

Characterization of the neutralizing activity of three anti-human TNF monoclonal antibodies and prediction of their TNF epitopes by molecular modeling and mutant protein approach

Cansheng Zhu, Xuesong Liu, Jiannan Feng, Wei Zhang, Beifen Shen, Weiming Ou’yang, Yunxin Cao, Boquan Jin

Journal:

Immunology Letters

Year:

2006

Language:

english

File:

PDF, 321 KB

english, 2006

12

Gene delivery GAD500 autoantigen by AAV serotype 1 prevented diabetes in NOD mice: Transduction efficiency do not play important roles

Gencheng Han, Renxi Wang, Guojiang Chen, Jianan Wang, Ruonan Xu, Jiannan Feng, Ming Yu, Xiaobing Wu, Jiahua Qian, Beifen Shen, Yan Li

Journal:

Immunology Letters

Year:

2008

Language:

english

File:

PDF, 211 KB

english, 2008

13

Suitable transmembrane domain significantly increase the surface-expression level of FcɛRIα in 293T cells

Chunxia Qiao, Leiming Guo, Jian Sun, Yan Li, Zhou Lin, Ming Lv, Jiannan Feng, Beifen Shen

Journal:

Journal of Biotechnology

Year:

2009

Language:

english

File:

PDF, 2.64 MB

english, 2009

14

STAT3 exerts two-way regulation in the biological effects of IL-6 in M1 leukemia cells

Jiyan Zhang, Beifen Shen, Yan Li, Yingxun Sun

Journal:

Leukemia Research

Year:

2001

Language:

english

File:

PDF, 421 KB

english, 2001

15

MEK inhibitor augments IL-6-induced growth arrest and apoptosis, but antagonizes IL-6-induced macrophage differentiation of M1 cells

Jiyan Zhang, Yan Li, Yingxun Sun, Beifen Shen

Journal:

Immunology Letters

Year:

2001

Language:

english

File:

PDF, 110 KB

english, 2001

16

Protein kinase ERK contributes to differential responsiveness of human myeloma cell lines to IFNα

Lun Song, Yan Li, Beifen Shen

Journal:

Cancer Cell International

Year:

2002

Language:

english

File:

PDF, 273 KB

english, 2002

17

PI3-K/Akt pathway contributes to IL-6-dependent growth of 7TD1 cells

JiYan Zhang, Yan Li, BeiFen Shen

Journal:

Cancer Cell International

Year:

2003

Language:

english

File:

PDF, 719 KB

english, 2003

18

Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX

Shaohua Li, Hua Xu, Hongmei Ding, Yanping Huang, Xiaoxiao Cao, Guang Yang, Jie Li, Zhigang Xie, Yuhong Meng, Xiaobing Li, Qiang Zhao, Beifen Shen, Ningsheng Shao

Journal:

The Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 617 KB

english, 2009

19

Construction of expression vectors and study on single-chain antibody and reshaping single-domain antibody against CD3

Xifu Liu, Sa Xiao, Zheng Gu, Yong Wang, Weiguo Zhang, Ai Chen, Qing Lin, Hualiang Huang, Jian Sun, Runsheng Chen, Beifen Shen, Xing Chen

Journal:

SCIENCE CHINA Life Sciences

Year:

1997

Language:

english

File:

PDF, 431 KB

english, 1997

20

Three-dimensional structure and function study on the active region in the extracellular ligand-binding domain of human IL-6 receptor

Yunfang Ren, Jiannan Feng, Hong Qu, Song Li, Beifen Shen

Journal:

SCIENCE CHINA Life Sciences

Year:

2000

Language:

english

File:

PDF, 343 KB

english, 2000

21

Prediction on the binding domain between human interleukin-6 and its receptor

Jiannan Feng, Yunfang Ren, Beifen Shen

Journal:

SCIENCE CHINA Life Sciences

Year:

2000

Language:

english

File:

PDF, 413 KB

english, 2000

22

Effects of inhibition of ubiquitin-proteasome pathway on human primary leukemic cells

Yu Lan, Xuemin Zhang, Pingdi Yang, Meiru Hu, Ming Yu, Yi Yang, Beifen Shen

Journal:

SCIENCE CHINA Life Sciences

Year:

2002

Language:

english

File:

PDF, 1.04 MB

english, 2002

23

cDNA cloning and function analysis of two novel erythroid differentiation related genes

Xin Wang, Duncheng Wang, Xing Chen, Meiru Hu, Jian’an Wang, Yan Li, Ning Guo, Beifen Shen

Journal:

SCIENCE CHINA Life Sciences

Year:

2001

Language:

english

File:

PDF, 587 KB

english, 2001

24

Initial function analysis of a novel erythroid differentiation related geneEDRF1

Duncheng Wang, Yan Li, Beifen Shen

Journal:

SCIENCE CHINA Life Sciences

Year:

2001

Language:

english

File:

PDF, 583 KB

english, 2001

25

Active regions’ setting of the extracellular ligandbinding domain of human interleukin-6 receptor

Yunfang Ren, Hong Qu, Jiannan Feng, Song Li, Beifen Shen

Journal:

Chinese Science Bulletin

Year:

2000

Language:

english

File:

PDF, 507 KB

english, 2000

26

Construction and analysis of three-dimensional graphic model of single-chain Fv derived from an anti-human placental acidic isoferritin monoclonal antibody by computer

Zhou Chun, Shen Guanxin, Zhu Huifen, Yang Jing, Zhang Yue, Feng Jiannan, Shen Beifen

Journal:

Journal of Huazhong University of Science and Technology -- Medical Sciences --

Year:

2000

Language:

english

File:

PDF, 457 KB

english, 2000

27

Identification of binding epitope of a monoclonal antibody (Z12) against human TNF-α using computer modeling and deletion mutant technique

Wei Zhang, Jiannan Feng, Beifen Shen

Journal:

SCIENCE CHINA Life Sciences

Year:

2004

Language:

english

File:

PDF, 2.41 MB

english, 2004

28

Expression and distribution of HSP27 in response to G418 in different human breast cancer cell lines

Lu Qian, Zhiyi Zhang, Ming Shi, Ming Yu, Meiru Hu, Qing Xia, Beifen Shen, Ning Guo

Journal:

Histochemistry and Cell Biology

Year:

2006

Language:

english

File:

PDF, 463 KB

english, 2006

29

Mutational analysis of ErbB2 intracellular localization

Liyong Chen, Lu Qian, Zhiyi Zhang, Ming Shi, Yuhua Song, Guogang Yuan, Hao Zhang, Meiru Hu, Ming Yu, Xuemin Zhang, Beifen Shen, Ning Guo

Journal:

Histochemistry and Cell Biology

Year:

2007

Language:

english

File:

PDF, 735 KB

english, 2007

30

Molecular Modeling and Affinity Determination of scFv Antibody: Proper Linker Peptide Enhances Its Activity

Xin Gu, Xiaoling Jia, Jiannan Feng, Beifen Shen, Ying Huang, Shusheng Geng, Yingxun Sun, Yugang Wang, Yan Li, Mian Long

Journal:

Annals of Biomedical Engineering

Year:

2010

Language:

english

File:

PDF, 617 KB

english, 2010

31

Changes of primary sequence and secondary structure proximal to the 5′ end of the stop codon substantially increases the expression of the variable region of an antibody inE. coli

Weisong Qin, Jiannan Feng, Yan Li, Zhou Lin, Beifen Shen

Journal:

Biotechnology Letters

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

32

Controlled Growth of Chinese Hamster Ovary Cells and High Expression of Antibody-IL-2 Fusion Proteins by Temperature Manipulation

Ming Shi, Zhigang Xie, Ming Yu, Beifen Shen, Ning Guo

Journal:

Biotechnology Letters

Year:

2005

Language:

english

File:

PDF, 211 KB

english, 2005

33

Expression, purification and characterization of soluble human interleukin-6 receptor α-chain and its mutant protein inEscherichia coli

Jing Wang, Zhenhui Yang, Ming Shi, Yan Li, Ning Guo, Beifen Shen, Jiannan Feng

Journal:

Biotechnology Letters

Year:

2007

Language:

english

File:

PDF, 301 KB

english, 2007

34

Novel chimeric anti-ricin antibody C4C13 with neutralizing activity against ricin toxicity

Yugang Wang, Leiming Guo, Kunpeng Zhao, Jugao Chen, Jiannan Feng, Yingxun Sun, Yan Li, Beifen Shen

Journal:

Biotechnology Letters

Year:

2007

Language:

english

File:

PDF, 313 KB

english, 2007

35

The β2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells

Ming Shi, Dan Liu, Huijun Duan, Lu Qian, Lina Wang, Lijia Niu, Huipeng Zhang, Zheng Yong, Zehui Gong, Lun Song, Ming Yu, Meiru Hu, Qing Xia, Beifen Shen, Ning Guo

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 645 KB

english, 2011

36

Structural-Based Rational Design of an Antagonist Peptide That Inhibits the Ribosome-Inactivating Activity of Ricin A Chain

Shuntao Wang, Jiannan Feng, Jianwei Guo, Yan Li, Yingxun Sun, Weisong Qin, Meiru Hu, Beifen Shen

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2005

Language:

english

File:

PDF, 383 KB

english, 2005

37

Heregulin-β promotes matrix metalloproteinase-7 expression via HER2-mediated AP-1 activation in MCF-7 cells

Guogang Yuan, Lu Qian, Lun Song, Ming Shi, Dan Li, Ming Yu, Meiru Hu, Beifen Shen, Ning Guo

Journal:

Molecular and Cellular Biochemistry

Year:

2008

Language:

english

File:

PDF, 365 KB

english, 2008

38

Rational design of potent mimic peptide derived from monoclonal antibody: antibody mimic design

Jiannan Feng, Yan Li, Wei Zhang, Beifen Shen

Journal:

Immunology Letters

Year:

2005

Language:

english

File:

PDF, 158 KB

english, 2005

39

CD8+ regulatory T cells are responsible for GAD-IgG gene-transferred tolerance induction in NOD mice

Renxi Wang, Gencheng Han, Lun Song, Jianan Wang, Guojiang Chen, Ruonan Xu, Ming Yu, Jiahua Qian, Beifen Shen, Yan Li

Journal:

Year:

2009

Language:

english

File:

PDF, 521 KB

english, 2009

40

Interleukin-17-producing γδ+ T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-β

Gencheng Han, Renxi Wang, Guojiang Chen, Jianan Wang, Ruonan Xu, Liyan Wang, Jiannan Feng, Xia Li, Renfeng Guo, Li Fu, Beifen Shen, Yan Li

Journal:

Year:

2010

Language:

english

File:

PDF, 471 KB

english, 2010

41

γδT-cell function in sepsis is modulated by C5a receptor signalling

Gencheng Han, Shaoxia Geng, Yurong Li, Guojiang Chen, Renxi Wang, Xinying Li, Yuanfang Ma, Beifen Shen, Yan Li

Journal:

Year:

2011

Language:

english

File:

PDF, 415 KB

english, 2011

42

C-terminus of TRAP in Staphylococcus can enhance the activity of lysozyme and lysostaphin

Guang Yang, Yaping Gao, Jiannan Feng, Yong Huang, Shaohua Li, Yu Liu, Chuan Liu, Ming Fan, Beifen Shen, Ningsheng Shao

Journal:

Acta Biochimica et Biophysica Sinica

Year:

2008

Language:

english

File:

PDF, 529 KB

english, 2008

43

cAMP Modulates Macrophage Development by Suppressing M-CSF-Induced MAPKs Activation

Zhu, Ning, Cui, Jian, Qiao, Chunxia, Li, Yan, Ma, Yuanfang, Zhang, Jiyan, Shen, Beifen

Journal:

Cellular & Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

44

Characterization of a Novel Anti-DR5 Monoclonal Antibody WD1 with the Potential to Induce Tumor Cell Apoptosis

Wang, Jing, Lin, Zhou, Qiao, Chunxia, Lv, Ming, Yu, Ming, Xiao, He, Wang, Qingyang, Wang, Liyan, Feng, Jiannan, Shen, Beifen

Journal:

Cellular & Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 512 KB

english, 2008

45

The Characteristic of an Anti-Human DR5 Antibody A6

Wang, Yugang, Zhao, Kunpeng, Chen, Jugao, Zhang, Jiyan, Yu, Ming, Li, Yan, Shen, Beifen

Journal:

Cellular & Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 363 KB

english, 2008

46

A soluble interleukin-6 receptor mutant inhibits interleukin-6-induced signal transduction in myeloma cells

Lun Song, Beifen Shen, Yunfang Ren

Journal:

Biotechnology Letters

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

47

A novel erythroid differentiation related geneEDRF2inhibited α-globin gene expression in K562 cells

Duncheng Wang, Xiaoming Yang, Beifen Shen

Journal:

Chinese Science Bulletin

Year:

2002

Language:

english

File:

PDF, 646 KB

english, 2002

48

Therapeutic effects of rhTNF alone and in combination with kengshengmycin in experimental human ovarian cancer

Zhao Enfeng, Zhou Meiqing, Fu Caiying, Shen Beifen, Zhang Quan, Lian Lijuan

Journal:

Chinese Journal of Cancer Research

Year:

1996

Language:

english

File:

PDF, 241 KB

english, 1996

49

Study of anti-CD9 and CD10 immunotoxins killing leukemic cells and the effect on hematopoiesis

Yan Li, Yonghuai He, Xing Chen, Yingxun Sun, Beifen Shen

Journal:

Chinese Journal of Cancer Research

Year:

1991

Language:

english

File:

PDF, 248 KB

english, 1991

50

The Peptide Derived from erbB2 Auto-Inhibitor Herstatin Shared in the Same Epitope and Function with Functional Antibody 2C4

Ming Lv, Chunxia Qiao, Nan Jiang, Xinying Li, Ming Yu, Chunmei Hou, Yan Li, Jiannan Feng, Beifen Shen

Journal:

Molecular Biotechnology

Year:

2012

Language:

english

File:

PDF, 879 KB

english, 2012